Research Article
Parkinson's Disease Diagnosis with I Ioflupane (DaTSCAN)
Issue:
Volume 12, Issue 4, August 2024
Pages:
40-55
Received:
20 August 2024
Accepted:
5 September 2024
Published:
23 September 2024
Abstract: The authors of the paper statistically evaluated the results of single photon emission computed tomography (SPECT) brain scans in 1050 patients with suspected Parkinson's disease. The control group consisted of patients with other neurological diseases who underwent SPECT brain scans. Diagnosis of Parkinson's disease based on clinical examination is not always straightforward. An examination of the transport dopaminergic route by Ioflupane (123I) helps to refine the diagnosis. Based on the obtained results, the authors believe that in the differential diagnosis of Parkinson's disease (or Parkinson's syndrome), SPECT brain imaging is of unmistakable importance, both from a clinical, therapeutic and socioeconomic point of view. In Parkinson's disease, the functional state of the autonomic nervous system (ANS) changes. Examination of the ANS can help both in the differential diagnosis of Parkinsonian syndromes and in determining the degree of impairment; it is a prognostic indicator. Results of Single Photon Emission Computed Tomography (SPECT) examinations were statistically evaluated in the group of 1050 patients with suspected Parkinson´s disease. SPECT examinations of patients with other neurological diseases were used as a control group. Diagnosis of Parkinson's disease based on clinical examination is not always straightforward. An examination of the transport dopaminergic route by Ioflupane (123I) helps to refine the diagnosis. After statistical evaluation of these results authors believe that in the differential diagnosis of Parkinson's disease (or Parkinson's syndrome), SPECT brain imaging is of huge importance from a clinical, therapeutic and socioeconomic point of view. In Parkinson's disease, the functional state of the autonomic nervous system changes. Examination of the autonomic nervous system can help both in the differential diagnosis and in determining the degree of impairment.
Abstract: The authors of the paper statistically evaluated the results of single photon emission computed tomography (SPECT) brain scans in 1050 patients with suspected Parkinson's disease. The control group consisted of patients with other neurological diseases who underwent SPECT brain scans. Diagnosis of Parkinson's disease based on clinical examination i...
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Research Article
A Retrospective View of Post Renal Transplant Urinary Tract Infections: An Experience of A UK Transplant Centre
Issue:
Volume 12, Issue 4, August 2024
Pages:
56-62
Received:
20 July 2024
Accepted:
11 September 2024
Published:
29 September 2024
Abstract: Urinary tract infections (UTIs) are prevalent post renal transplant complication. These infections are most common in renal transplant recipient’s contrary to their incidence in general healthy population as shown by previous studies. Though the frequencies of occurrences are different in renal transplant patients. There is general lack of consensus on the risk factors associated with development of UTIs in renal transplant patients as well as effects posed by them and occurrence of mortality in patient group. This retrospective cohort study investigated and included adults’ patients who were operated for renal transplant in a single transplant center in UK from Jan 2014 to December 2023. The number of patients were 604 with two hundred and fifty-nine developed one or more UTIs in 42 months follow-up period. Significant risk factors for post-transplant UTIs were advanced age, female gender, reflux kidney disease, use of azathioprine and cadaveric donor. UTIs did not increase risk for renal graft loss, but were associated with increased mortality (3.5 odds ratio, 95% confidence interval 1.68–7.23). We conclude UTIs may be associated with an increased mortality risk in renal transplant recipients. Prevention of UTIs in high-risk renal transplant patients or those with recurrent UTIs may possibly decrease post-transplant mortality.
Abstract: Urinary tract infections (UTIs) are prevalent post renal transplant complication. These infections are most common in renal transplant recipient’s contrary to their incidence in general healthy population as shown by previous studies. Though the frequencies of occurrences are different in renal transplant patients. There is general lack of consensu...
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,
Stefan Madarasz
